20-Hydroxyecdysone is an ecdysteroid hormone produced in arthropod species that induces developmental changes associated with ecdysis and the completion of metamorphosis.{26314} It is also produced in plants as a defensive strategy to disrupt the development of insect pests.{26312} In target tissues, 20-hydroxyecdysone binds to the nuclear hormone receptor, ecdysone receptor, initiating a signaling cascade that results in cell cycle arrest.{26314,26313} Ecdysteroids such as this compound have been employed as tools in inducible gene regulation systems controlled by reporter cells transfected with the ecdysone receptor.{26316,26315}
产品描述
An ecdysteroid hormone produced in arthropod species that induces developmental changes associated with ecdysis and the completion of metamorphosis; used as a tool in inducible gene regulation systems controlled by reporter cells transfected with the ecdysone receptor